GlutaredoxinV1, Main, Exploration, bibRecord, 001367

An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.

Identifieur interne : 001367 ( Main/Exploration ); précédent : 001366; suivant : 001368

An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.

Auteurs : K. Axelsson ; B. Mannervik

Source :

FEBS letters [ 0014-5793 ] ; 1983.

RBID : pubmed:6840271

Descripteurs français

KwdFr :
- Animaux (MeSH), Cytosol (enzymologie), Foie (enzymologie), Glutarédoxines (MeSH), Glutathion (métabolisme), Glutathione reductase (métabolisme), Oxidoreductases (métabolisme), Oxydoréduction (MeSH), Protein-disulfide reductase (glutathione) (MeSH), Pyruvate kinase (métabolisme), Rats (MeSH).
MESH :
- enzymologie : Cytosol, Foie.
- métabolisme : Glutathion, Glutathione reductase, Oxidoreductases, Pyruvate kinase.
- Animaux, Glutarédoxines, Oxydoréduction, Protein-disulfide reductase (glutathione), Rats.

English descriptors

KwdEn :
- Animals (MeSH), Cytosol (enzymology), Glutaredoxins (MeSH), Glutathione (metabolism), Glutathione Reductase (metabolism), Liver (enzymology), Oxidation-Reduction (MeSH), Oxidoreductases (metabolism), Protein Disulfide Reductase (Glutathione) (MeSH), Pyruvate Kinase (metabolism), Rats (MeSH).
MESH :
- chemical , metabolism : Glutathione, Glutathione Reductase, Oxidoreductases, Pyruvate Kinase.
- chemical : Glutaredoxins, Protein Disulfide Reductase (Glutathione).
- enzymology : Cytosol, Liver.
- Animals, Oxidation-Reduction, Rats.

Abstract

Pyruvate kinase from rabbit liver is inactivated spontaneously in the presence of air. Glutathione in physiological concentrations gives partial protection against inactivation. Full protection is obtained with glutathione and purified cytosolic thioltransferase supplemented with a glutathione-regenerating system. It is suggested that thioltransferase plus glutathione serve a general function in protecting protein thiol groups against oxidation.

DOI: 10.1016/0014-5793(83)80494-3
PubMed: 6840271

Affiliations:

Links toward previous steps (curation, corpus...)

to stream Main, to step Corpus: 001366
to stream Main, to step Curation: 001366

Le document en format XML

<record><TEI><teiHeader><fileDesc><titleStmt><title xml:lang="en">An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.</title>
<author><name sortKey="Axelsson, K" sort="Axelsson, K" uniqKey="Axelsson K" first="K" last="Axelsson">K. Axelsson</name>
</author>
<author><name sortKey="Mannervik, B" sort="Mannervik, B" uniqKey="Mannervik B" first="B" last="Mannervik">B. Mannervik</name>
</author>
</titleStmt>
<publicationStmt><idno type="wicri:source">PubMed</idno>
<date when="1983">1983</date>
<idno type="RBID">pubmed:6840271</idno>
<idno type="pmid">6840271</idno>
<idno type="doi">10.1016/0014-5793(83)80494-3</idno>
<idno type="wicri:Area/Main/Corpus">001366</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Corpus" wicri:corpus="PubMed">001366</idno>
<idno type="wicri:Area/Main/Curation">001366</idno>
<idno type="wicri:explorRef" wicri:stream="Main" wicri:step="Curation">001366</idno>
<idno type="wicri:Area/Main/Exploration">001366</idno>
</publicationStmt>
<sourceDesc><biblStruct><analytic><title xml:lang="en">An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.</title>
<author><name sortKey="Axelsson, K" sort="Axelsson, K" uniqKey="Axelsson K" first="K" last="Axelsson">K. Axelsson</name>
</author>
<author><name sortKey="Mannervik, B" sort="Mannervik, B" uniqKey="Mannervik B" first="B" last="Mannervik">B. Mannervik</name>
</author>
</analytic>
<series><title level="j">FEBS letters</title>
<idno type="ISSN">0014-5793</idno>
<imprint><date when="1983" type="published">1983</date>
</imprint>
</series>
</biblStruct>
</sourceDesc>
</fileDesc>
<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Animals (MeSH)</term>
<term>Cytosol (enzymology)</term>
<term>Glutaredoxins (MeSH)</term>
<term>Glutathione (metabolism)</term>
<term>Glutathione Reductase (metabolism)</term>
<term>Liver (enzymology)</term>
<term>Oxidation-Reduction (MeSH)</term>
<term>Oxidoreductases (metabolism)</term>
<term>Protein Disulfide Reductase (Glutathione) (MeSH)</term>
<term>Pyruvate Kinase (metabolism)</term>
<term>Rats (MeSH)</term>
</keywords>
<keywords scheme="KwdFr" xml:lang="fr"><term>Animaux (MeSH)</term>
<term>Cytosol (enzymologie)</term>
<term>Foie (enzymologie)</term>
<term>Glutarédoxines (MeSH)</term>
<term>Glutathion (métabolisme)</term>
<term>Glutathione reductase (métabolisme)</term>
<term>Oxidoreductases (métabolisme)</term>
<term>Oxydoréduction (MeSH)</term>
<term>Protein-disulfide reductase (glutathione) (MeSH)</term>
<term>Pyruvate kinase (métabolisme)</term>
<term>Rats (MeSH)</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="metabolism" xml:lang="en"><term>Glutathione</term>
<term>Glutathione Reductase</term>
<term>Oxidoreductases</term>
<term>Pyruvate Kinase</term>
</keywords>
<keywords scheme="MESH" type="chemical" xml:lang="en"><term>Glutaredoxins</term>
<term>Protein Disulfide Reductase (Glutathione)</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymologie" xml:lang="fr"><term>Cytosol</term>
<term>Foie</term>
</keywords>
<keywords scheme="MESH" qualifier="enzymology" xml:lang="en"><term>Cytosol</term>
<term>Liver</term>
</keywords>
<keywords scheme="MESH" qualifier="métabolisme" xml:lang="fr"><term>Glutathion</term>
<term>Glutathione reductase</term>
<term>Oxidoreductases</term>
<term>Pyruvate kinase</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Animals</term>
<term>Oxidation-Reduction</term>
<term>Rats</term>
</keywords>
<keywords scheme="MESH" xml:lang="fr"><term>Animaux</term>
<term>Glutarédoxines</term>
<term>Oxydoréduction</term>
<term>Protein-disulfide reductase (glutathione)</term>
<term>Rats</term>
</keywords>
</textClass>
</profileDesc>
</teiHeader>
<front><div type="abstract" xml:lang="en">Pyruvate kinase from rabbit liver is inactivated spontaneously in the presence of air. Glutathione in physiological concentrations gives partial protection against inactivation. Full protection is obtained with glutathione and purified cytosolic thioltransferase supplemented with a glutathione-regenerating system. It is suggested that thioltransferase plus glutathione serve a general function in protecting protein thiol groups against oxidation.</div>
</front>
</TEI>
<pubmed><MedlineCitation Status="MEDLINE" Owner="NLM"><PMID Version="1">6840271</PMID>
<DateCompleted><Year>1983</Year>
<Month>06</Month>
<Day>10</Day>
</DateCompleted>
<DateRevised><Year>2019</Year>
<Month>06</Month>
<Day>21</Day>
</DateRevised>
<Article PubModel="Print"><Journal><ISSN IssnType="Print">0014-5793</ISSN>
<JournalIssue CitedMedium="Print"><Volume>152</Volume>
<Issue>1</Issue>
<PubDate><Year>1983</Year>
<Month>Feb</Month>
<Day>07</Day>
</PubDate>
</JournalIssue>
<Title>FEBS letters</Title>
<ISOAbbreviation>FEBS Lett</ISOAbbreviation>
</Journal>
<ArticleTitle>An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.</ArticleTitle>
<Pagination><MedlinePgn>114-8</MedlinePgn>
</Pagination>
<Abstract><AbstractText>Pyruvate kinase from rabbit liver is inactivated spontaneously in the presence of air. Glutathione in physiological concentrations gives partial protection against inactivation. Full protection is obtained with glutathione and purified cytosolic thioltransferase supplemented with a glutathione-regenerating system. It is suggested that thioltransferase plus glutathione serve a general function in protecting protein thiol groups against oxidation.</AbstractText>
</Abstract>
<AuthorList CompleteYN="Y"><Author ValidYN="Y"><LastName>Axelsson</LastName>
<ForeName>K</ForeName>
<Initials>K</Initials>
</Author>
<Author ValidYN="Y"><LastName>Mannervik</LastName>
<ForeName>B</ForeName>
<Initials>B</Initials>
</Author>
</AuthorList>
<Language>eng</Language>
<PublicationTypeList><PublicationType UI="D016428">Journal Article</PublicationType>
<PublicationType UI="D013485">Research Support, Non-U.S. Gov't</PublicationType>
</PublicationTypeList>
</Article>
<MedlineJournalInfo><Country>England</Country>
<MedlineTA>FEBS Lett</MedlineTA>
<NlmUniqueID>0155157</NlmUniqueID>
<ISSNLinking>0014-5793</ISSNLinking>
</MedlineJournalInfo>
<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
<NameOfSubstance UI="D054477">Glutaredoxins</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.-</RegistryNumber>
<NameOfSubstance UI="D010088">Oxidoreductases</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.8.1.7</RegistryNumber>
<NameOfSubstance UI="D005980">Glutathione Reductase</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 1.8.4.2</RegistryNumber>
<NameOfSubstance UI="D011490">Protein Disulfide Reductase (Glutathione)</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>EC 2.7.1.40</RegistryNumber>
<NameOfSubstance UI="D011770">Pyruvate Kinase</NameOfSubstance>
</Chemical>
<Chemical><RegistryNumber>GAN16C9B8O</RegistryNumber>
<NameOfSubstance UI="D005978">Glutathione</NameOfSubstance>
</Chemical>
</ChemicalList>
<CitationSubset>IM</CitationSubset>
<MeshHeadingList><MeshHeading><DescriptorName UI="D000818" MajorTopicYN="N">Animals</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D003600" MajorTopicYN="N">Cytosol</DescriptorName>
<QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D054477" MajorTopicYN="N">Glutaredoxins</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005978" MajorTopicYN="N">Glutathione</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D005980" MajorTopicYN="N">Glutathione Reductase</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="N">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D008099" MajorTopicYN="N">Liver</DescriptorName>
<QualifierName UI="Q000201" MajorTopicYN="N">enzymology</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010084" MajorTopicYN="N">Oxidation-Reduction</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D010088" MajorTopicYN="N">Oxidoreductases</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011490" MajorTopicYN="Y">Protein Disulfide Reductase (Glutathione)</DescriptorName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D011770" MajorTopicYN="N">Pyruvate Kinase</DescriptorName>
<QualifierName UI="Q000378" MajorTopicYN="Y">metabolism</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName UI="D051381" MajorTopicYN="N">Rats</DescriptorName>
</MeshHeading>
</MeshHeadingList>
</MedlineCitation>
<PubmedData><History><PubMedPubDate PubStatus="pubmed"><Year>1983</Year>
<Month>2</Month>
<Day>7</Day>
</PubMedPubDate>
<PubMedPubDate PubStatus="medline"><Year>1983</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>0</Hour>
<Minute>1</Minute>
</PubMedPubDate>
<PubMedPubDate PubStatus="entrez"><Year>1983</Year>
<Month>2</Month>
<Day>7</Day>
<Hour>0</Hour>
<Minute>0</Minute>
</PubMedPubDate>
</History>
<PublicationStatus>ppublish</PublicationStatus>
<ArticleIdList><ArticleId IdType="pubmed">6840271</ArticleId>
<ArticleId IdType="pii">0014-5793(83)80494-3</ArticleId>
<ArticleId IdType="doi">10.1016/0014-5793(83)80494-3</ArticleId>
</ArticleIdList>
</PubmedData>
</pubmed>
<affiliations><list></list>
<tree><noCountry><name sortKey="Axelsson, K" sort="Axelsson, K" uniqKey="Axelsson K" first="K" last="Axelsson">K. Axelsson</name>
<name sortKey="Mannervik, B" sort="Mannervik, B" uniqKey="Mannervik B" first="B" last="Mannervik">B. Mannervik</name>
</noCountry>
</tree>
</affiliations>
</record>

Pour manipuler ce document sous Unix (Dilib)

EXPLOR_STEP=$WICRI_ROOT/Bois/explor/GlutaredoxinV1/Data/Main/Exploration

HfdSelect -h $EXPLOR_STEP/biblio.hfd -nk 001367 | SxmlIndent | more

HfdSelect -h $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd -nk 001367 | SxmlIndent | more

Pour mettre un lien sur cette page dans le réseau Wicri

{{Explor lien
   |wiki=    Bois
   |area=    GlutaredoxinV1
   |flux=    Main
   |étape=   Exploration
   |type=    RBID
   |clé=     pubmed:6840271
   |texte=   An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.
}}

Pour générer des pages wiki

HfdIndexSelect -h $EXPLOR_AREA/Data/Main/Exploration/RBID.i   -Sk "pubmed:6840271" \
       | HfdSelect -Kh $EXPLOR_AREA/Data/Main/Exploration/biblio.hfd   \
       | NlmPubMed2Wicri -a GlutaredoxinV1

This area was generated with Dilib version V0.6.37.
Data generation: Wed Nov 18 15:13:42 2020. Site generation: Wed Nov 18 15:16:12 2020

	Serveur d'exploration sur la glutarédoxine
	Attention, ce site est en cours de développement ! Attention, site généré par des moyens informatiques à partir de corpus bruts. Les informations ne sont donc pas validées.

Serveur d'exploration sur la glutarédoxine

An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.

An essential role of cytosolic thioltransferase in protection of pyruvate kinase from rabbit liver against oxidative inactivation.

Source :

Descripteurs français

English descriptors

Abstract

Links toward previous steps (curation, corpus...)

Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

Pour mettre un lien sur cette page dans le réseau Wicri

Pour générer des pages wiki